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"I think individuals are drawn to a quick, simple repair, type of a magic bullet supplement, and it's not that this will not add to weight reduction, however it's not that magic bullet," Griffin says. Langer sums it up this way: "You need to put the effort in," she says. "If you desire to remain in ketosis, do the ketogenic diet.

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Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects. Regul Toxicol Pharmacol. 2012; 63( 3 ):401 -8. View abstract. Cox PJ, Kirk T, Ashmore T, et al. Nutritional ketosis modifies fuel preference and therefore endurance performance in professional athletes. Cell Metab. 2016; 24( 2 ):256 -68. View abstract. Evans M, Cogan KE, Egan B. Metabolism of ketone bodies during workout and training: physiological basis for exogenous supplements.

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Surgery. 1991; 109( 2 ):176 -81. View abstract. Holdsworth DA, Cox PJ, Kirk T, Stradling H, Impey SG, Clarke K. A ketone ester beverage increases postexercise muscle glycogen synthesis in people. Med Sci Sports Exerc. 2017; 49( 9 ):1789 -1795. View abstract. Kawakita T, Uchino M, Fukagawa K, et al. Randomized, multicenter, double-blind research study of the security and effectiveness of 1%D-3-hydroxybutyrate eye drops for dry eye illness.

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2016; 6:20855. View abstract. Kemper MF, Srivastava S, Todd King M, Clarke K, Veech RL, Pawlosky RJ. An ester of -hydroxybutyrate regulates cholesterol biosynthesis in rats and a cholesterol biomarker in humans.  A Reliable Source ( 12 ):1185 -93. View abstract. Mc, Nally MA, Hartman AL. Ketone bodies in epilepsy. J Neurochem. 2012; 121( 1 ):28 -35. View abstract. Newman JC, Verdin E.